Physical and chemical barriers

The body's first lines of defense are the skin and mucous membranes, which prevent the entrance of many pathogens.

There are many secondary barriers.

For example, tears, sweat, and saliva combat some bacteria, and the hydrochloric acid and protein-digesting enzymes secreted by the stomach are lethal to many, but not all, pathogens (Janeway CA et al 1999; Beers MB 2004).

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