Glutathione -powerful antioxidant found within every cell

Glutathione - or L Glutathione - is a powerful antioxidant found within every cell. Glutathione plays a role in nutrient metabolism, and regulation of cellular events (including gene expression, DNA and protein synthesis, cell growth, and immune response.

This antioxidant, made from the combination of three amino acids cysteine, glutamate, and glycine, forms part of the powerful natural antioxidant glutathione peroxidase which is found in our cells.

Glutathione peroxidase plays a variety of roles in cells, including DNA synthesis and repair, metabolism of toxins and carcinogens, enhancement of the immune system, and prevention of fat oxidation.

However, glutathione is predominantly known as an antioxidant protecting our cells from damage caused by the free radical hydrogen peroxide.

Glutathione also helps the other antioxidants in cells stay in their active form.

Brain glutathione levels have been found to be lower in patients with Parkinson’s disease.

Parkinson's Disease

Parkinson’s disease is a common neurological condition afflicting about 1 percent of men and women over the age of seventy. In Parkinson’s disease, a small region in the brain, called the substantia nigra, begins to deteriorate. The neurons of the substantia nigra use the brain chemical dopamine. With the loss of dopamine, tremors begin and movement slows. Despite current drug therapies, Parkinson’s disease remains a progressive and incurable condition. Many patients with Parkinson’s disease may also suffer from age related cognitive decline or have some of the symptoms of Alzheimer’s disease.

GSH has five major functions

Antioxidant:
Antioxidant is a substance that neutralizes destructive free radicals; some are manufactured by the metabolic processes of the body, others are derived from foods, the air we breath, exercise, stress and disease.GSH is the most powerful Antioxidant occurring naturally in the cells of the body. Through its significant reducing power, GSH also makes major contributions to the recycling of other Antioxidant that have become oxidized. Healthy cells homeostatically oppose free radicals through the use of Antioxidant, of which GSH plays a significant role. The effectiveness of other Antioxidant like vitamins C and E depends on the availability of GSH.

Help Prevent Disease:
Oxidative related diseases: accelerated aging, cell destruction, causes damage to DNA cellular patterns which leads to cancer, arteriosclerosis, coronary artery disease, Parkinson’s disease, diseases of the immune system, diabetes, cataract formation, Alzheimer’s, macular degeneration, COPD, allergy/asthma, stroke.

Detoxification:
GSH also plays a main role in detoxification..primarily in Phase II Liver detox. It "binds" to many toxins by its sulfur molecules and aids in forming a complex which the body then rids itself of.

Immune System Support:
When the immune system responds to an invader, it releases a blitz of free radicals to aid in the offensive agent's demise. This could create damage to local tissue and your body, but GSH rallies around the area to quench the free radicals that are produced in excess.

Protection from Radiation:
A recent research article published in the journal Radiology states that “radiation from a single whole-body scan is equal to that from 100 mammograms and is similar to that received by survivors of the atomic bombings of Hiroshima and Nagasaki, Japan – about 1 mile from the explosions – according to radiation biologist, David J. Brenner of Columbia University. The radiation from one scan is enough to produce a tumor in one out of 1200 people, and for those who have annual scans the risk increases to one tumor in every 50 people. With inadequate intracellular GSH the risk is greatly increased.

Substances that Boost Glutathione Levels and Protect Brain Cells

Taking Glutathione itself as a supplement does not boost cellular Glutathione levels, since it breaks down in the digestive tract before it reaches the cells.

However, intravenous Glutathione therapy and Glutathione precursors or dietary supplements are effective in boosting intracellular levels ofGlutathione.

Intravenous Glutathione Injections:
Intravenous Glutathione injections have been shown to produce amazing and rapid results, in patients with Parkinson's disease. Followingeven a single dosage of intravenous Glutathione, many of the symptoms of Parkinson's disease rapidly improve, often in as little as 15 minutes.

Glutathione Precursors:
In the Alzheimer's study conducted by Welsh GP, Andrew McCaddon, adding theGlutathione precursor, N-acetyl-cysteine (NAC) to a protocol thatlowered homocysteine levels by simple supplementation with B12 and folate, resulted in prompt, striking, and sustained clinical improvement in nearly all the patients.

Cucurmin (turmeric):
Studies have shown that the Indian curry spice, cucurmin, has neuroprotective effects because of its ability to induce the enzyme, hemeoxygenase-1(HO-1), which protects neurons exposed to oxidant stress. Treatment of brain cells called astrocytes, with curcumin, increases expression of HO-1 protein as well as Glutathione S-transferase.

Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7919-24. Epub 2003 Jun 05.
Am J Geriatr Psychiatry. 2003 Mar-Apr;11(2):246-9
Can Curry Protect Against Alzheimer's?; American Physiological Society (APS) Press Release; 16-Apr-2004

Glutathione's three major roles in the body are summarized by the letters A-B-C.
- Anti-oxidant- Blood Booster- Cell Detoxifier


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