Glutathione plays an important role in our ear nose throat eyes (ENT) health.
The primary way everything enters our body both good and bad is through the ear nose throat eyes. Actually our eyes are a secondary portal of entry.
The things entering can be good such as breathing, sound and food. It can also be potentially damaging to the body. These include toxins, bacteria's, viruses, and carcinogens. It would only seem natural that the human body would have a defense systems to protect the points of entry.
The good news...it does. It is called the immune system. It is a formidable military force. The strongest front line defense is the marine like tripeptide glutathione. It is not only in each cell, it is in the respiratory tract lining fluid (RTLF). Glutathione is the main antioxidant in this fluid.
Click here for more about Glutathione and its benefits to our body.
The Upper Respiratory Tract
It depletes with age
The weakest point of the human body would be the place of greatest risk of attack by infection and toxins. Glutathione is the primary defense for the nose and throat.
General Otolaryngology
LaryngitisParotitis (inflammation of the parotid gland)
Pharyngitis (inflammation of the pharynx producing symptoms similar to tonsillitis)
Sleep apneaSnoringTonsillitis (inflammation of tonsils producing pain)
odynophagia (painful swallowing fever etc)
HyperthyroidismThyroid cancer
Sore throat
Strep throat
Esophageal cancer
Click here for more about Glutathione and its benefits to our body.
Showing posts with label inflammation. Show all posts
Showing posts with label inflammation. Show all posts
Tuesday, February 12, 2008
Thursday, February 7, 2008
Sources and Effects of Oxidants
Four endogenous sources appear to account for most of the oxidants produced by cells:
1) As a consequence of normal aerobic respiration, mitochondria consume molecular oxygen, reducing it by sequential steps to produce H20. Inevitable by-products of this process, as stated above, are O2.-, H202, and .OH. About l012 oxygen molecules are processed by each rat cell daily, and the leakage of partially reduced oxygen molecules is about 2%, yielding about 2x1010 superoxide and hydrogen peroxide molecules per cell per day.
2) Phagocytic cells destroy bacteria or virus-infected cells with an oxidative burst of NO, O2.-, H2O2, and [[macron]]OCl. Chronic infection by viruses, bacteria, or parasites, results in a chronic phagocytic activity and consequent chronic inflammation, which is a major risk factor for cancer. Chronic infections are particularly prevalent in third world countries.
3) Peroxisomes, which are organelles responsible for degrading fatty acids and other molecules, produce H202 as a byproduct, which is then degraded by catalase. Evidence suggests that, under certain conditions, some of the peroxide escapes degradation, resulting in its release into other compartments of the cell and in increased oxidative DNA damage.
4) Cytochrome P450 enzymes in animals constitute one of the primary defense systems against natural toxic chemicals from plants, the major source of dietary toxins. The induction of these enzymes, prevent acute toxic effects from foreign chemicals, but also results in oxidant by-products that damage DNA (Park, J.-Y. K. and Ames, B.N., unpublished).
Click here for more about Glutathione and its benefits to our body.
Three exogenous sources may significantly increase the large endogenous oxidant load.
1) The oxides of nitrogen (NOx) in cigarette smoke (about 1000 ppm) cause oxidation of macromolecules, and deplete antioxidant levels. This is likely to contribute significantly to the pathology of smoking. Smoking is a risk factor for heart disease as well as a wide variety of cancers in addition to lung cancer.
2) Iron (and copper) salts promote the generation of oxidizing radicals from peroxides (Fenton chemistry). Men who absorb significantly more than normal amounts of dietary iron due to a genetic defect (hemochromatosis disease) are at an increased risk for both cancer and heart disease. It has therefore been argued that too much dietary copper or iron, particularly heme iron (which is high in meat), is a risk factor for cardiovascular disease and cancer in normal men
3) Normal diets contain plant food with large amounts of natural phenolic compounds, such as chlorogenic and caffeic acid, that may generate oxidants by redox cycling .
Click here for more about Glutathione and its benefits to our body.
1) As a consequence of normal aerobic respiration, mitochondria consume molecular oxygen, reducing it by sequential steps to produce H20. Inevitable by-products of this process, as stated above, are O2.-, H202, and .OH. About l012 oxygen molecules are processed by each rat cell daily, and the leakage of partially reduced oxygen molecules is about 2%, yielding about 2x1010 superoxide and hydrogen peroxide molecules per cell per day.
2) Phagocytic cells destroy bacteria or virus-infected cells with an oxidative burst of NO, O2.-, H2O2, and [[macron]]OCl. Chronic infection by viruses, bacteria, or parasites, results in a chronic phagocytic activity and consequent chronic inflammation, which is a major risk factor for cancer. Chronic infections are particularly prevalent in third world countries.
3) Peroxisomes, which are organelles responsible for degrading fatty acids and other molecules, produce H202 as a byproduct, which is then degraded by catalase. Evidence suggests that, under certain conditions, some of the peroxide escapes degradation, resulting in its release into other compartments of the cell and in increased oxidative DNA damage.
4) Cytochrome P450 enzymes in animals constitute one of the primary defense systems against natural toxic chemicals from plants, the major source of dietary toxins. The induction of these enzymes, prevent acute toxic effects from foreign chemicals, but also results in oxidant by-products that damage DNA (Park, J.-Y. K. and Ames, B.N., unpublished).
Click here for more about Glutathione and its benefits to our body.
Three exogenous sources may significantly increase the large endogenous oxidant load.
1) The oxides of nitrogen (NOx) in cigarette smoke (about 1000 ppm) cause oxidation of macromolecules, and deplete antioxidant levels. This is likely to contribute significantly to the pathology of smoking. Smoking is a risk factor for heart disease as well as a wide variety of cancers in addition to lung cancer.
2) Iron (and copper) salts promote the generation of oxidizing radicals from peroxides (Fenton chemistry). Men who absorb significantly more than normal amounts of dietary iron due to a genetic defect (hemochromatosis disease) are at an increased risk for both cancer and heart disease. It has therefore been argued that too much dietary copper or iron, particularly heme iron (which is high in meat), is a risk factor for cardiovascular disease and cancer in normal men
3) Normal diets contain plant food with large amounts of natural phenolic compounds, such as chlorogenic and caffeic acid, that may generate oxidants by redox cycling .
Click here for more about Glutathione and its benefits to our body.
Wednesday, February 6, 2008
Inflammation, Free Radicals, and Cytokines
Although acute Inflammation is an important immune system response, chronic inflammation has also been linked to many diseases, including heart disease. Besides the pro-Inflammation cytokines, Inflammation may be related to the overproduction of free radicals (Janeway CA et al 1999).
A free radical is an atom or group of atoms (i.e., a molecule) with unpaired electrons. Free radicals are extremely unstable and react easily with other molecules, thereby changing their chemical composition. Oxygen is especially susceptible to free radical formation. The free radicals derived from oxygen are known as reactive oxygen species, or oxidants.
When the body has increased levels of reactive oxygen species (i.e., when it is experiencing oxidative stress), widespread damage may result. At high concentrations free radicals can damage fats, proteins, and nucleic acids. They can also cause cell death, gene mutations, and cancer ( Moslen MT 1994). Several diseases may be the result of cellular and genetic damage caused by free radicals, including several immune disorders ( Moslen MT 1994).
In order to reduce the damage caused by elevated free radicals and cytokines (which are both part of the natural immune system), the body fights back by producing antioxidants and hormones such as cortisol to suppress the immune system (Grimble RF 1996). Antioxidants are valuable because they pair with unstable free radicals, thereby limiting the damage free radicals can inflict on other cells.
Click here for more about Glutathione and its benefits to our body.
A free radical is an atom or group of atoms (i.e., a molecule) with unpaired electrons. Free radicals are extremely unstable and react easily with other molecules, thereby changing their chemical composition. Oxygen is especially susceptible to free radical formation. The free radicals derived from oxygen are known as reactive oxygen species, or oxidants.
When the body has increased levels of reactive oxygen species (i.e., when it is experiencing oxidative stress), widespread damage may result. At high concentrations free radicals can damage fats, proteins, and nucleic acids. They can also cause cell death, gene mutations, and cancer ( Moslen MT 1994). Several diseases may be the result of cellular and genetic damage caused by free radicals, including several immune disorders ( Moslen MT 1994).
In order to reduce the damage caused by elevated free radicals and cytokines (which are both part of the natural immune system), the body fights back by producing antioxidants and hormones such as cortisol to suppress the immune system (Grimble RF 1996). Antioxidants are valuable because they pair with unstable free radicals, thereby limiting the damage free radicals can inflict on other cells.
Click here for more about Glutathione and its benefits to our body.
Inflammation and fever
Inflammation is a nonspecific response to infection or tissue injury. The four signs of the inflammatory response are redness, swelling, heat, and pain.
Inflammation begins when cells release certain cytokines, including interleukin (IL)-1, IL-6, and tumor necrosis factor-alpha (TNF-alpha ) (Janeway CA et al 1999; Beers MB 2004).
Inflammation is a process by which the body’s white blood cells and chemicals protect us from infection and foreign substances such as bacteria and viruses.
In some diseases, however, the body’s defense system (immune system) inappropriately triggers an Inflammation response when there are no foreign substances to fight off. In these diseases, called autoimmune diseases, the body’s normally protective immune system causes damage to its own tissues. The body responds as if normal tissues are infected or somehow abnormal.
Click here for more information about Glutathione and its benefits in our immune system.
Inflammation begins when cells release certain cytokines, including interleukin (IL)-1, IL-6, and tumor necrosis factor-alpha (TNF-alpha ) (Janeway CA et al 1999; Beers MB 2004).
Inflammation is a process by which the body’s white blood cells and chemicals protect us from infection and foreign substances such as bacteria and viruses.
In some diseases, however, the body’s defense system (immune system) inappropriately triggers an Inflammation response when there are no foreign substances to fight off. In these diseases, called autoimmune diseases, the body’s normally protective immune system causes damage to its own tissues. The body responds as if normal tissues are infected or somehow abnormal.
Click here for more information about Glutathione and its benefits in our immune system.
Sunday, February 3, 2008
Parkinson's Disease Diagnosis
It is difficult to diagnose Parkinson’s disease in the early stages. Early on, Parkinson’s disease is diagnosed almost primarily by its symptoms, and studies indicate that physicians make an incorrect initial diagnosis of Parkinson’s disease in between 10% and 40% of cases. Blood tests are not helpful for diagnosis.
Parkinson’s disease is just one of several neurologic movement disorders that produce similar symptoms.
It is important that the physician you are seeing has experience with all of the different disorders that can masquerade as Parkinson’s disease.
In some of these diseases people quickly become totally disabled; in others, the disease progresses extremely slowly; and in yet others, illness is chronic (always present) and may have more severe symptoms as time goes on. Because the natural history, or progression, of these diseases varies greatly, proper diagnosis is crucial. People need to know which disease they have.
The Neurologic Examination
When performing a neurologic examination to evaluate a patient with a movement disorder, the doctor takes a medical history and performs a physical examination. The doctor asks the patient and the family members or friends about symptoms and observes the patient, asking him or her to walk around the room, sit down, stand up, turn around, and so on.
Diagnostic Tests
Unfortunately, there is no diagnostic test that can confirm Parkinson’s disease. Laboratory testing of the blood of patients with the symptoms typical of Parkinson’s disease only rarely uncovers any abnormality.
Electroencephalograms (EEGs) record some aspects of brain electrical activity, but they are not effective in spotting Parkinson’s disease.
Important Roles of Glutathione
Fight against oxidative cell damage (Free Radicals)• Protein Synthesis• Amino Acid transport• Cellular detoxification• Immune system enhancement• Enzyme activation• Fight Inflammation• ATP (energy) production
Our cells are constantly under attack by Free Radicals, which can cause a reduction of our cells ability to function optimally.
Click here for more about Glutathione and its benefits to our body.
Parkinson’s disease is just one of several neurologic movement disorders that produce similar symptoms.
It is important that the physician you are seeing has experience with all of the different disorders that can masquerade as Parkinson’s disease.
In some of these diseases people quickly become totally disabled; in others, the disease progresses extremely slowly; and in yet others, illness is chronic (always present) and may have more severe symptoms as time goes on. Because the natural history, or progression, of these diseases varies greatly, proper diagnosis is crucial. People need to know which disease they have.
The Neurologic Examination
When performing a neurologic examination to evaluate a patient with a movement disorder, the doctor takes a medical history and performs a physical examination. The doctor asks the patient and the family members or friends about symptoms and observes the patient, asking him or her to walk around the room, sit down, stand up, turn around, and so on.
Diagnostic Tests
Unfortunately, there is no diagnostic test that can confirm Parkinson’s disease. Laboratory testing of the blood of patients with the symptoms typical of Parkinson’s disease only rarely uncovers any abnormality.
Electroencephalograms (EEGs) record some aspects of brain electrical activity, but they are not effective in spotting Parkinson’s disease.
Important Roles of Glutathione
Fight against oxidative cell damage (Free Radicals)• Protein Synthesis• Amino Acid transport• Cellular detoxification• Immune system enhancement• Enzyme activation• Fight Inflammation• ATP (energy) production
Our cells are constantly under attack by Free Radicals, which can cause a reduction of our cells ability to function optimally.
Click here for more about Glutathione and its benefits to our body.
Tuesday, January 22, 2008
Exercise builds brain health: key roles of growth factor cascades and inflammation
Human and other animal studies demonstrate that exercise targets many aspects of brain function and has broad effects on overall brain health.
The benefits of exercise have been best defined for learning and memory, protection from neurodegeneration and alleviation of depression, particularly in elderly populations.
Exercise increases synaptic plasticity by directly affecting synaptic structure and potentiating synaptic strength, and by strengthening the underlying systems that support plasticity including neurogenesis, metabolism and vascular function.
Such exercise-induced structural and functional change has been documented in various brain regions but has been best-studied in the hippocampus - the focus of this review.
A key mechanism mediating these broad benefits of exercise on the brain is induction of central and peripheral growth factors and growth factor cascades, which instruct downstream structural and functional change.
In addition, exercise reduces peripheral risk factors such as diabetes, hypertension and cardiovascular disease, which converge to cause brain dysfunction and neurodegeneration.
A common mechanism underlying the central and peripheral effects of exercise might be related to inflammation, which can impair growth factor signaling both systemically and in the brain.
Thus, through regulation of growth factors and reduction of peripheral and central risk factors, exercise ensures successful brain function.
by: Carl W Cotman, Nicole C Berchtold, Lori-Ann Christie
Trends in Neurosciences, Vol. 30, No. 9. (September 2007), pp. 464-472
Important Roles of Glutathione
Fight against oxidative cell damage (Free Radicals)
• Protein Synthesis
• Amino Acid transport
• Cellular detoxification
• Immune system enhancement
• Enzyme activation
• Fight Inflammation
• ATP (energy) production
Our cells are constantly under attack by Free Radicals, which can cause a reduction of our cells ability to function optimally.
Click here for more about Glutathione and its benefits to our body.
The benefits of exercise have been best defined for learning and memory, protection from neurodegeneration and alleviation of depression, particularly in elderly populations.
Exercise increases synaptic plasticity by directly affecting synaptic structure and potentiating synaptic strength, and by strengthening the underlying systems that support plasticity including neurogenesis, metabolism and vascular function.
Such exercise-induced structural and functional change has been documented in various brain regions but has been best-studied in the hippocampus - the focus of this review.
A key mechanism mediating these broad benefits of exercise on the brain is induction of central and peripheral growth factors and growth factor cascades, which instruct downstream structural and functional change.
In addition, exercise reduces peripheral risk factors such as diabetes, hypertension and cardiovascular disease, which converge to cause brain dysfunction and neurodegeneration.
A common mechanism underlying the central and peripheral effects of exercise might be related to inflammation, which can impair growth factor signaling both systemically and in the brain.
Thus, through regulation of growth factors and reduction of peripheral and central risk factors, exercise ensures successful brain function.
by: Carl W Cotman, Nicole C Berchtold, Lori-Ann Christie
Trends in Neurosciences, Vol. 30, No. 9. (September 2007), pp. 464-472
Important Roles of Glutathione
Fight against oxidative cell damage (Free Radicals)
• Protein Synthesis
• Amino Acid transport
• Cellular detoxification
• Immune system enhancement
• Enzyme activation
• Fight Inflammation
• ATP (energy) production
Our cells are constantly under attack by Free Radicals, which can cause a reduction of our cells ability to function optimally.
Click here for more about Glutathione and its benefits to our body.
Monday, January 21, 2008
Dr. Robert Keller and Glutathione
Robert Keller MD, MS, FACP, has been named as one of the world’s 2,000 Outstanding Scientists of the 21st Century, and has served on the scientific review panels for the National Institutes of Health and the VA.
The Consumers’ Research Council has named Dr. Keller one of America’s “Top Physicians in 2003, 2004, 2005, 2006, and 2007 in the fields of Internal Medicine, Immunology and Hematology.
Dr. Keller has served on the faculties of the Mayo Graduate School of Medicine, the University of Wisconsin and the Medical College of Wisconsin (Marquette Univ.) He has published more than 100 original articles in various scientific and medical journals and has been awarded several patents.
Dr Keller was elected to The Board of Governors of the American Academy of HIV medicine.
Read Robert H. Keller, MD, MS, FACP, AAHIVS CurriculmVitae
Dr. Robert H. Keller, one of the world’s leading scientists dedicated 10 years of research and development into MaxGXL to assist the world in its quest for a higher quality of health.Out of all the biological processes that Dr Keller could have focused his attention on, he chose to investigate a way to naturally optimize the body’s production of glutathione.
Glutathione is a fairly tricky word, but your body relies on its function every single day.
Important Roles of Glutathione
• Fight against oxidative cell damage (Free Radicals)
• Protein Synthesis
• Amino Acid transport
• Cellular detoxification
• Immune system enhancement
• Enzyme activation
• Fight Inflammation
• ATP (energy) production
Our cells are constantly under attack by Free Radicals, which can cause a reduction of our cells ability to function optimally.
Click here for more about Glutathione and its benefits to our body.
The Consumers’ Research Council has named Dr. Keller one of America’s “Top Physicians in 2003, 2004, 2005, 2006, and 2007 in the fields of Internal Medicine, Immunology and Hematology.
Dr. Keller has served on the faculties of the Mayo Graduate School of Medicine, the University of Wisconsin and the Medical College of Wisconsin (Marquette Univ.) He has published more than 100 original articles in various scientific and medical journals and has been awarded several patents.
Dr Keller was elected to The Board of Governors of the American Academy of HIV medicine.
Read Robert H. Keller, MD, MS, FACP, AAHIVS CurriculmVitae
Dr. Robert H. Keller, one of the world’s leading scientists dedicated 10 years of research and development into MaxGXL to assist the world in its quest for a higher quality of health.Out of all the biological processes that Dr Keller could have focused his attention on, he chose to investigate a way to naturally optimize the body’s production of glutathione.
Glutathione is a fairly tricky word, but your body relies on its function every single day.
Important Roles of Glutathione
• Fight against oxidative cell damage (Free Radicals)
• Protein Synthesis
• Amino Acid transport
• Cellular detoxification
• Immune system enhancement
• Enzyme activation
• Fight Inflammation
• ATP (energy) production
Our cells are constantly under attack by Free Radicals, which can cause a reduction of our cells ability to function optimally.
Click here for more about Glutathione and its benefits to our body.
Friday, January 18, 2008
How much glutathione is enough?
Unfortunately, there is no Recommended Dietary Allowance (RDA) for glutathione to indicate how much is enough.
One hundred milligrams each day is the usual recommended dosage for glutathione.
THE MAX GXL is a PATENTED High Performance Formula which:
Dramatically Raises Your Energy Level
Slows Down The Aging Process
Strengthens Your Immune System
Fights Inflammation and Diseases of Aging
Improves Athletic Performance & Recovery
Detoxifies Your Body
One hundred milligrams each day is the usual recommended dosage for glutathione.
THE MAX GXL is a PATENTED High Performance Formula which:
Dramatically Raises Your Energy Level
Slows Down The Aging Process
Strengthens Your Immune System
Fights Inflammation and Diseases of Aging
Improves Athletic Performance & Recovery
Detoxifies Your Body
Thursday, January 17, 2008
Glutathione, stress responses, and redox signaling in lung inflammation
Changes in the ratio of intracellular reduced and disulfide forms ofGlutathione (GSH/GSSG) can affect signaling pathways that participate in various physiological responses from cell proliferation to gene expression and apoptosis.
It is also now known that many proteins have a highly conserved cysteine (sulfhydryl) sequence in their active/regulatory sites, which are primary targets of oxidative modifications and thus important components of redox signaling.
However, the mechanism by which oxidants and GSH/protein-cysteine-thiols actually participate in redox signaling still remains to be elucidated.
Initial studies involving the role of cysteine in various proteins have revealed that cysteine-SH may mediate redox signaling via reversible or irreversible oxidative modification to Cys-sulfenate or Cys-sulfinate and Cys-sulfonate species, respectively.
Oxidative stress possibly via the modification of cysteine residues activates multiple stress kinase pathways and transcription factors nuclear factor-kappaB and activator protein-1, which differentially regulate the genes for proinflammatory cytokines as well as the protective antioxidant genes. Understanding the redox signaling mechanisms for differential gene regulation may allow for the development of novel pharmacological approaches that preferentially up-regulate key antioxidant genes, which, in turn, reduce or resolve inflammation and injury.
This forum article features the current knowledge on the role of GSH in redox signaling, particularly the regulation of transcription factors and downstream signaling in lung inflammation. Rahman I , Biswas SK , Jimenez LA , Torres M , Forman HJ
Glutathione's three major roles in the body are summarized by the letters A-B-C.- Anti-oxidant- Blood Booster- Cell Detoxifier
It is also now known that many proteins have a highly conserved cysteine (sulfhydryl) sequence in their active/regulatory sites, which are primary targets of oxidative modifications and thus important components of redox signaling.
However, the mechanism by which oxidants and GSH/protein-cysteine-thiols actually participate in redox signaling still remains to be elucidated.
Initial studies involving the role of cysteine in various proteins have revealed that cysteine-SH may mediate redox signaling via reversible or irreversible oxidative modification to Cys-sulfenate or Cys-sulfinate and Cys-sulfonate species, respectively.
Oxidative stress possibly via the modification of cysteine residues activates multiple stress kinase pathways and transcription factors nuclear factor-kappaB and activator protein-1, which differentially regulate the genes for proinflammatory cytokines as well as the protective antioxidant genes. Understanding the redox signaling mechanisms for differential gene regulation may allow for the development of novel pharmacological approaches that preferentially up-regulate key antioxidant genes, which, in turn, reduce or resolve inflammation and injury.
This forum article features the current knowledge on the role of GSH in redox signaling, particularly the regulation of transcription factors and downstream signaling in lung inflammation. Rahman I , Biswas SK , Jimenez LA , Torres M , Forman HJ
Glutathione's three major roles in the body are summarized by the letters A-B-C.- Anti-oxidant- Blood Booster- Cell Detoxifier
Wednesday, January 16, 2008
Substances that Boost Glutathione Levels and Protect Brain Cells
Taking Glutathione itself as a supplement does not boost cellular Glutathione levels, since it breaks down in the digestive tract before it reaches the cells.
However, intravenous Glutathione therapy and Glutathione precursors or dietary supplements are effective in boosting intracellular levels ofGlutathione.
Intravenous Glutathione Injections:
Intravenous Glutathione injections have been shown to produce amazing and rapid results, in patients with Parkinson's disease. Followingeven a single dosage of intravenous Glutathione, many of the symptoms of Parkinson's disease rapidly improve, often in as little as 15 minutes.
Glutathione Precursors:
In the Alzheimer's study conducted by Welsh GP, Andrew McCaddon, adding theGlutathione precursor, N-acetyl-cysteine (NAC) to a protocol thatlowered homocysteine levels by simple supplementation with B12 and folate, resulted in prompt, striking, and sustained clinical improvement in nearly all the patients.
Cucurmin (turmeric):
Studies have shown that the Indian curry spice, cucurmin, has neuroprotective effects because of its ability to induce the enzyme, hemeoxygenase-1(HO-1), which protects neurons exposed to oxidant stress. Treatment of brain cells called astrocytes, with curcumin, increases expression of HO-1 protein as well as Glutathione S-transferase.
Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7919-24. Epub 2003 Jun 05.
Am J Geriatr Psychiatry. 2003 Mar-Apr;11(2):246-9
Can Curry Protect Against Alzheimer's?; American Physiological Society (APS) Press Release; 16-Apr-2004
Glutathione's three major roles in the body are summarized by the letters A-B-C.
- Anti-oxidant- Blood Booster- Cell Detoxifier
THE MAX GXL is a PATENTED High Performance Formula which:
Dramatically Raises Your Energy Level
Slows Down The Aging Process
Strengthens Your Immune System
Fights Inflammation and Diseases of Aging
Improves Athletic Performance & Recovery
Detoxifies Your Body
However, intravenous Glutathione therapy and Glutathione precursors or dietary supplements are effective in boosting intracellular levels ofGlutathione.
Intravenous Glutathione Injections:
Intravenous Glutathione injections have been shown to produce amazing and rapid results, in patients with Parkinson's disease. Followingeven a single dosage of intravenous Glutathione, many of the symptoms of Parkinson's disease rapidly improve, often in as little as 15 minutes.
Glutathione Precursors:
In the Alzheimer's study conducted by Welsh GP, Andrew McCaddon, adding theGlutathione precursor, N-acetyl-cysteine (NAC) to a protocol thatlowered homocysteine levels by simple supplementation with B12 and folate, resulted in prompt, striking, and sustained clinical improvement in nearly all the patients.
Cucurmin (turmeric):
Studies have shown that the Indian curry spice, cucurmin, has neuroprotective effects because of its ability to induce the enzyme, hemeoxygenase-1(HO-1), which protects neurons exposed to oxidant stress. Treatment of brain cells called astrocytes, with curcumin, increases expression of HO-1 protein as well as Glutathione S-transferase.
Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7919-24. Epub 2003 Jun 05.
Am J Geriatr Psychiatry. 2003 Mar-Apr;11(2):246-9
Can Curry Protect Against Alzheimer's?; American Physiological Society (APS) Press Release; 16-Apr-2004
Glutathione's three major roles in the body are summarized by the letters A-B-C.
- Anti-oxidant- Blood Booster- Cell Detoxifier
THE MAX GXL is a PATENTED High Performance Formula which:
Dramatically Raises Your Energy Level
Slows Down The Aging Process
Strengthens Your Immune System
Fights Inflammation and Diseases of Aging
Improves Athletic Performance & Recovery
Detoxifies Your Body
Thursday, January 10, 2008
Glutathione, Liver Health, Cystic Fibrosis and Lung Health
Hepatitis C is characterized by decreased mitochondrialGlutathione and increased mitochondrial susceptibility to free radicals.
Furthermore, Glutathione deficiency is common in liver cirrhosis patients and hepatitis patients.
Cystic Fibrosis and Lung Health New findings suggest that cystic fibrosis mutations lead to Glutathione deficiency in the epithelial lining fluid of the lung and in immune system cells and the gastrointestinal tract.
This deficiency increases over time as the higher-than-normal oxidant burden of cystic fibrosis leads to successively larger glutathione decrements without the normal opportunity to fully recover physiologic levels.
This Glutathione deficiency may be the trigger for initial depletion of other antioxidants and may also initiate the excessive inflammation found in cystic fibrosis. According to the researchers, “In a way, cystic fibrosis may be thought of as the first identified disease with Glutathione system dysfunction.” Researchers have notedGlutathionedepletion in lung epithelial lining fluid in other respiratory diseases such as chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis, and adult respiratory distress syndrome. The study authors concluded, “Therapies to augment Glutathione may also be contemplated in these diseases.” By Priya F. Shah
Click here for more about Glutathione and its benefits to our body.
Furthermore, Glutathione deficiency is common in liver cirrhosis patients and hepatitis patients.
Cystic Fibrosis and Lung Health New findings suggest that cystic fibrosis mutations lead to Glutathione deficiency in the epithelial lining fluid of the lung and in immune system cells and the gastrointestinal tract.
This deficiency increases over time as the higher-than-normal oxidant burden of cystic fibrosis leads to successively larger glutathione decrements without the normal opportunity to fully recover physiologic levels.
This Glutathione deficiency may be the trigger for initial depletion of other antioxidants and may also initiate the excessive inflammation found in cystic fibrosis. According to the researchers, “In a way, cystic fibrosis may be thought of as the first identified disease with Glutathione system dysfunction.” Researchers have notedGlutathionedepletion in lung epithelial lining fluid in other respiratory diseases such as chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis, and adult respiratory distress syndrome. The study authors concluded, “Therapies to augment Glutathione may also be contemplated in these diseases.” By Priya F. Shah
Click here for more about Glutathione and its benefits to our body.
Wednesday, January 9, 2008
How can Glutathione help in the Treatment of Infertility?
Glutathione is not only vital to sperm antioxidant defenses, but selenium and Glutathione are essential to the formation of "phospholipid hydroperoxide Glutathione peroxidase" - an enzyme present in spermatids - which becomes a structural protein in the mid-piece of mature spermatozoa.
When either substance is deficient, it can lead to instability of the mid-piece of the spermatozoa, resulting in defective motility.
Free radical scavengers - such as Glutathione - that restore the structure and function of poly-unsaturated fatty acids (PUFA) in the cell membrane, can be used to treat these cases.
In a double-blind cross-over study of twenty infertile men, treatment with Glutathione led to a statistically significant improvement of the sperm quality.
The study concerned men in whom the sperm quality was poor due to unilateral varicocele or germ-free genital tract inflammation - two conditions in which ROS or other toxic compounds are indicated as causative factors.
Treatment with Glutathione was also found to have a statistically significantly positive effect on sperm motility (in particular forward motility) and on sperm morphology. The findings of these studies indicate that Glutathione therapy could represent a possible therapeutical tool in cases where ROS or exposure to toxins is the probable cause of infertility.
By Priya F. Shah
Click here for more about Glutathione and its benefits to our body.
When either substance is deficient, it can lead to instability of the mid-piece of the spermatozoa, resulting in defective motility.
Free radical scavengers - such as Glutathione - that restore the structure and function of poly-unsaturated fatty acids (PUFA) in the cell membrane, can be used to treat these cases.
In a double-blind cross-over study of twenty infertile men, treatment with Glutathione led to a statistically significant improvement of the sperm quality.
The study concerned men in whom the sperm quality was poor due to unilateral varicocele or germ-free genital tract inflammation - two conditions in which ROS or other toxic compounds are indicated as causative factors.
Treatment with Glutathione was also found to have a statistically significantly positive effect on sperm motility (in particular forward motility) and on sperm morphology. The findings of these studies indicate that Glutathione therapy could represent a possible therapeutical tool in cases where ROS or exposure to toxins is the probable cause of infertility.
By Priya F. Shah
Click here for more about Glutathione and its benefits to our body.
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