Glutathione helps to support the proper functioning of your immune system , and will improve immune system already in retreat.
Glutathione acts as an powerful antioxidant and Free radicals scavenger, thereby protecting our DNA and RDA from damage due to many environmental factors.
Glutathione acts as the regulator of other powerful antioxidant.
Glutathione acts as a detoxifying agent, removing foreign objects, chemicals and toxins from the body. As you age, your levels of Glutathione are depleted, thereby allowing the aging process to accelerate.
Levels of Glutathione can be sucessfully improved by taking a high quality nutritional supplement!
***Among the uses that have been reported for glutathione are:
treatment of poisoning, particularly heavy metal poisons
treatment of idiopathic pulmonary firbosis
increasing the effectiveness and reducing the toxicity of cis-platinum, a chemo drug used to treat breast cancer
treating Parkinson's disease
lowering blood pressure in patients with diabetes
increasing male sperm counts in humans and animals
treatment of liver cancer
treatment of sickle cell anemia
http://www.healthline.com/galecontent/glutathione
Click here for more about Glutathione and its benefits to our body.
Showing posts with label immune cells. Show all posts
Showing posts with label immune cells. Show all posts
Thursday, February 7, 2008
Wednesday, February 6, 2008
Phagocytic cells
Phagocytic cells engulf foreign cells and destroy them. The phagocytic cells are white blood cells and include neutrophils, eosinophils, and macrophages; they have short lives and must be continually replenished by the body. Neutrophils and macrophages are a very important aspect of the innate defenses of the body (Janeway CA et al 1999; Beers MB 2004).
Click here for more information about Glutathione and its benefits in our immune system.
More study:
Polymorphonuclear leukocytes isolated from chicken peritoneal exudates have been found to catalyze cyanide-insensitive stimulation of respiration and the hexose monophosphate shunt upon exposure to heat-inactivated Staphylococcus aureus.
However, there was no demonstrable formate oxidation concomitant with phagocytosis in either the presence or absence of exogenous catalase. Moreover, chicken polymorphonuclear leukocytes failed to oxidize scopoletin concomitant with phagocytosis in the presence of horseradish peroxidase. While oxygen uptake was increased 2- to 3-fold by the stimulus of phagocytosis, the oxidation of [1-(14)C]glucose was increased approximately 20-fold.
The cells contain two mechanisms, a Glutathione reductase-Glutathione peroxidase system and an NADPH-NAD+ transhydrogenase, each of which is present in sufficient capacity to accommodate the enhanced shunt activity.
Although chicken polymorphonuclear leukocytes were found to possess a substantial capacity to catalyze the cyanide-insensitive oxidation of either NADH or NADPH, the total or specific activities of such processes were not demonstrably affected by phagocytosis.
Click here for more information about Glutathione and its benefits in our immune system.
Click here for more information about Glutathione and its benefits in our immune system.
More study:
Polymorphonuclear leukocytes isolated from chicken peritoneal exudates have been found to catalyze cyanide-insensitive stimulation of respiration and the hexose monophosphate shunt upon exposure to heat-inactivated Staphylococcus aureus.
However, there was no demonstrable formate oxidation concomitant with phagocytosis in either the presence or absence of exogenous catalase. Moreover, chicken polymorphonuclear leukocytes failed to oxidize scopoletin concomitant with phagocytosis in the presence of horseradish peroxidase. While oxygen uptake was increased 2- to 3-fold by the stimulus of phagocytosis, the oxidation of [1-(14)C]glucose was increased approximately 20-fold.
The cells contain two mechanisms, a Glutathione reductase-Glutathione peroxidase system and an NADPH-NAD+ transhydrogenase, each of which is present in sufficient capacity to accommodate the enhanced shunt activity.
Although chicken polymorphonuclear leukocytes were found to possess a substantial capacity to catalyze the cyanide-insensitive oxidation of either NADH or NADPH, the total or specific activities of such processes were not demonstrably affected by phagocytosis.
Click here for more information about Glutathione and its benefits in our immune system.
The Immune System
The immune system is an elegant and complex set of components that combine to fight disease, infections, and various pathogens. A healthy immune system distinguishes organisms in the body as “self” or “non-self.” An intact immune response identifies pathogens as “non-self” and rapidly destroys them. A depressed immune system, by contrast, will allow invading organisms to flourish.
Furthermore, when the immune system mistakenly recognizes a “self” cell as “non-self” and mounts an immune response, the result is an autoimmune disorder such as rheumatoid arthritis.
In general, the body has two primary defense mechanisms: natural immunity and acquired immunity. Natural immunity is the “first responder” to an attack. The natural immune response relies on various white blood cells and physical barriers to block or immediately attack any foreign invader and attempt to destroy it.
Acquired immunity, on the other hand, involves antibodies that are created in response to specific foreign antigens. This sort of response requires a few days for the body to recognize the invader and manufacture antibodies against it. Once the body has manufactured a particular antibody for a specific invader, the immune system response is faster and more effective the next time that invader appears (Janeway CA et al 1999; Beers MB 2004).
Click here for more information about Glutathione and its benefits in our immune system.
Furthermore, when the immune system mistakenly recognizes a “self” cell as “non-self” and mounts an immune response, the result is an autoimmune disorder such as rheumatoid arthritis.
In general, the body has two primary defense mechanisms: natural immunity and acquired immunity. Natural immunity is the “first responder” to an attack. The natural immune response relies on various white blood cells and physical barriers to block or immediately attack any foreign invader and attempt to destroy it.
Acquired immunity, on the other hand, involves antibodies that are created in response to specific foreign antigens. This sort of response requires a few days for the body to recognize the invader and manufacture antibodies against it. Once the body has manufactured a particular antibody for a specific invader, the immune system response is faster and more effective the next time that invader appears (Janeway CA et al 1999; Beers MB 2004).
Click here for more information about Glutathione and its benefits in our immune system.
Raised Glutathione Levels Help Balance Immune System
Researchers from Germany and the US have found that Glutathione can boost the natural antioxidant system of the body.
The body carries many antioxidant defense systems, but inside cells a small protein called glutathione is crucial. Glutathione is essential for the function of immune cells, which protect us from viral and bacterial infections.
In people with immune deficiency, glutathione levels fall well below the normal levels in blood and immune cells. Restoring glutathione levels to those found in healthy people is likely to help immune deficient patients.
Two studies have recently been published with research backing up the claims that Glutathione helps fight disease, one in the European Journal of Clinical Investigation, from Stig Froland in Oslo, Norway, and the other by Leonore and Leonard Herzenberg, a husband and wife team from Stanford, California. The results of their work showed that glutathione levels could indeed be restored in AIDS patients and that this may improve the outlook for these patients.
Herzenberg and colleagues conducted a clinical trial in which 31 HIV-infected patients were given daily doses of Glutathione — and 30 others were given a benign sugar pill. According to the study published in the October 1 issue of the European Journal of Clinical Investigation, those taking Glutathione had increased the amount of glutathione in their bodies to near-normal levels at the end of the two-month trial.
“The importance here is that glutathione is a central component of all cells, and glutathione deficiency is associated with poor prognosis in many, many diseases,” said Herzenberg. “What we’ve proven is that giving people Glutathione replenishes the glutathione stores.”
The authors of the report concluded that “Glutathione offers useful adjunct therapy to increase protection against oxidative stress, improve immune system function and increase detoxification of acetaminophen and other drugs. These findings suggest Glutathione therapy could be valuable in other clinical situations in which there is GSH deficiency.”
“It is important to realize that these results are the culmination of over 10 years of research.” states Frank Staal, an immunologist from Rotterdam, The Netherlands, who worked in this field for many years. “The groups of Droge and Herzenberg were the first to demonstrate that Glutathione is low in AIDS and that this defect contributes to poor immune cell function." ImmuneSupport.com
Click here for more about Glutathione and its benefits to our body.
The body carries many antioxidant defense systems, but inside cells a small protein called glutathione is crucial. Glutathione is essential for the function of immune cells, which protect us from viral and bacterial infections.
In people with immune deficiency, glutathione levels fall well below the normal levels in blood and immune cells. Restoring glutathione levels to those found in healthy people is likely to help immune deficient patients.
Two studies have recently been published with research backing up the claims that Glutathione helps fight disease, one in the European Journal of Clinical Investigation, from Stig Froland in Oslo, Norway, and the other by Leonore and Leonard Herzenberg, a husband and wife team from Stanford, California. The results of their work showed that glutathione levels could indeed be restored in AIDS patients and that this may improve the outlook for these patients.
Herzenberg and colleagues conducted a clinical trial in which 31 HIV-infected patients were given daily doses of Glutathione — and 30 others were given a benign sugar pill. According to the study published in the October 1 issue of the European Journal of Clinical Investigation, those taking Glutathione had increased the amount of glutathione in their bodies to near-normal levels at the end of the two-month trial.
“The importance here is that glutathione is a central component of all cells, and glutathione deficiency is associated with poor prognosis in many, many diseases,” said Herzenberg. “What we’ve proven is that giving people Glutathione replenishes the glutathione stores.”
The authors of the report concluded that “Glutathione offers useful adjunct therapy to increase protection against oxidative stress, improve immune system function and increase detoxification of acetaminophen and other drugs. These findings suggest Glutathione therapy could be valuable in other clinical situations in which there is GSH deficiency.”
“It is important to realize that these results are the culmination of over 10 years of research.” states Frank Staal, an immunologist from Rotterdam, The Netherlands, who worked in this field for many years. “The groups of Droge and Herzenberg were the first to demonstrate that Glutathione is low in AIDS and that this defect contributes to poor immune cell function." ImmuneSupport.com
Click here for more about Glutathione and its benefits to our body.
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